NOVEL FLUORINATED POLY (LACTIC-CO-GLYCOLIC ACID) (PLGA) AND POLYETHYLENE GLYCOL (PEG) NANOPARTICLES FOR MONITORING AND IMAGING IN OSTEOARTHRITIS

Novel Fluorinated Poly (Lactic-Co-Glycolic acid) (PLGA) and Polyethylene Glycol (PEG) Nanoparticles for Monitoring and Imaging in Osteoarthritis

Polymeric nanoparticles (NPs) find many uses in nanomedicine, from drug delivery to imaging.In this regard, poly (lactic-co-glycolic acid) (PLGA) and polyethylene glycol (PEG) particles are the most widely applied types of nano-systems due to their biocompatibility and biodegradability.Here we developed novel fluorinated polymeric NPs as vectors fo

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MD SIMULATION STUDIES TO INVESTIGATE ISO-ENERGETIC CONFORMATIONAL BEHAVIOUR OF MODIFIED NUCLEOSIDES M2G AND M22G PRESENT IN tRNA

Modified nucleic acid bases are most commonly found in tRNA.These may contain modifications from simple methylation to addition of bulky groups.Methylation of the four canonical nucleotide bases at a wide variety of positions is particularly prominent among the known modification.Methylation of N2 group of guanine is a relatively common modificatio

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